American Association of Neuropathologists
Volume 11, Number 3     November, 2000

     Rubinstein Award
     Weil Award
     Moore Award
Annual Meeting Information
     2000 ANNUAL MEETING--Atlanta, GA
     Business Meeting
     Diagnostic Slide Session
     Highlights of the Atlanta Meeting
     Highlights of the 2001 Chicago Meeting
     Special Course
     Scientific Sessions
     Saul R. Korey Lecture
     Diagnostic Slide Session
     Presidential Symposium
     Business Meeting
     Hotel Reservations and Meeting Registration
     Future AANP Meetings

AANP News Items
     Abstract Submission Goes Electronic
     Membership Directory to go Online
     International Society News
     Seventh European NP Congress Announced
     AANP to Host XVIth International Congress in 2006
     Professional Affairs Update
     CME Notices
     CME Updates
     Reception Surprise
Membership Information
     New Members and Changes in Membership Status
AANP & Newsletter Information
     Other Executive Council Members
     Committee Chairs
     Journal & Newsletter


Winners of the Rubinstein Award for the best paper in neuro-oncology were G. N. Fuller, K. R. Hess, C. H. Rhee, J. M. Bruner, R. A. Sawaya, W. K. A. Yung, and W. Zhang from the University of Texas MD Anderson Cancer Center for their presentation Molecular classification of human gliomas by gene expression profiling (Abstract #13). Honorable Mention of the Rubinstein Award was awarded to P. E. North, A. Mizeracki, M. Waner, M Mihm, and R. E. Mrak, from the University of Arkansas Medical Sciences, for their paper Do juvenile hemangiomas originate from endoneurial microvasculature? (Abstract #39).

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The Weil Award for the best paper in experimental neuropathology was awarded to L. Refolo, K. Duff, B. Malester, J. LaFrancois, R. Wang, K. Sambamurti, G. S. Tint, T. Thomas, and M. A. Pappolla for their presentation Hypercholesterolemia accelerates amyloid accumulation in a transgenic mouse model of Alzheimer's Disease (Abstract #20). Honorable Mention for the Weil Award was given to W. G. Tourtellotte, C. P. Keller-Peck, J. Kucera, W. D. Snider, and J. D. Milbrandt, from Northwestern University for their paper Gamma, but not alpha, spinal motor neurons require glial cell line-derived neurotrophic factor (GDNF) for their survival in vivo (Abstract #136).

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The Moore Award for the best clinicopathological correlation was presented to A. Messing, A. B. Johnson, O. Boespflug-Tanguy, D. Rodriguez, J. E. Goldman, and M. Brenner for Mutations of GFAP associated with Alexander Disease (Abstract #143). Honorable Mention was awarded to T. W Smith, O. Sanchez, and M. Ramzan for their paper Subacute diencephalic angioencephal-opathy with extensive brainstem involvement (Abstract #43).

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Minutes enclosed.

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Case summaries and discussions enclosed.

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The Seventy-sixth Annual Meeting of the American Association of Neuropathologists was held at the SHERATON ATLANTA Hotel in Atlanta, Georgia from June 8-11, 2000.

The special course, The Hippocampus in Health and Disease, organized by President Suzanne S. Mirra and Bradley T. Hyman, included lectures by Drs. Gary W. Van Hoesen, Bradley T. Hyman, Dennis W. Dickson, Ronald C. Petersen, Carol A. Barnes, Larry R. Squire, and Dawna L. Armstrong.

The Saul Korey Lecture, Neuropathology and Forensic Pathology: A Natural Synergism, was given by Dr. Mary Case.

The Presidential Symposium included the Presidential Address by Dr. Mirra, entitled The Neuropathology of Alzheimer's Disease: A Gray Matter. Dr. Seymour Benzer, the Matthew T. Moore Distinguished Lecturer, spoke on The Neuropathology of Drosophila. Other lecturers in the Presidential Symposium were Dr. Douglas C. Wallace and Dr. Maria Grazia Spillantini who discussed Mitochondrial Genetics and Neurodegeneration and Tau, AlphaSynuclein, and Neurodegeneration, respectively.

Dr. William R. Markesbery was honored as the recipient of the 2000 Meritorious Service Award to Neuropathology. A total of 198 abstracts were presented at the meeting's scientific sessions.

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The special course for the 2001 meeting, entitled Developmental Neurobiology has been organized by President Stephen J. DeArmond. The Course will provide an update on the molecular biology and cell biology of nervous system development and differentiation and to discuss relevant clinical disorders as related to abnormalities of development. An outstanding roster of speakers has been assembled and ample time for questions and discussion will be available. The program will include the following topics and lecturers:

Patterning of CNS & Axon Guidance
Dennis D. O'Leary (San Diego, CA)
Molecular Control of Neuronal Migration
Thomas Curran (Memphis, TN)
CDC kinase and Neurodegeneration
Li-Huei Tsai (Boston, MA)
Molecular Mechanism of Forebrain Development
Jeffrey A. Golden (Philadelphia, PA)
Neurotrophins ­ Window to Neuronal Functions
Louis F. Reichardt (San Francisco, CA)
Transcriptional Control of Neuronal Survival &Differentiation
Eric Huang (San Francisco, CA)
Developmental Abnormalities of the Nervous System in Human & Animal Models
Harvey B. Sarnat (Seattle, WA)

The American Association of Neuropathologists is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians and designates the above continuing medical education activity for 7 credit hours in Category 1 of the Physician's Recognition Award of the American Medical Association.


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Concurrent platform and poster sessions will be held all day Friday and Saturday, June 22-23, 2001. The program will provide up-to-date developments in all areas of experimental, research and practical neuropathology.


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Professor Paul Kleihues, Lyon, France, has been selected as the next Saul R. Korey lecturer. Dr. Kleihues' lecture, entitled Molecular Biology of Brain Tumors, promises to provide an up-to-date review of this important topic.


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The popular annual diagnostic slide session will be held at 8:00 PM on Saturday, June 23. Suitable cases for the Diagnostic Slide Session are being sought. If you have a case that you would like to present, please send the slides and a clinical summary to:

E. Tessa Hedley-Whyte, M.D.
Massachusetts General Hospital
14 Fruit Street
Boston, MA 02114-2696
Ph: 617- 726-5154

If your case is selected, it will be necessary to provide 150 slides for distribution. Cases will be selected before February 1, 2001.

Protocols for the Diagnostic Slide Session will be available without charge at the meeting. For additional information, please contact Dr. Leroy Sharer at 973- 972-4770.

Beginning with the Chicago 2001 meeting, attendance at the Diagnostic Slide Session will qualify for an additional 3 credit hours in Category I.


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President Stephen J. DeArmond has been organizing a stimulating Sunday morning symposium. Dr. DeArmond's Presidential Address will be entitled Mechanisms of Degeneration in Prion Diseases. In addition, Dr. Douglas C. Wallace (Atlanta, GA) will speak on Mitochondrial Mechanisms of Neurodegeneration, and Dr. Ralph A. Nixon (New York, NY) on Lysosomal Mechanisms of Neurodegeneration. As part of the Symposium, the Matthew T. Moore Distinguished Lecture, entitled Receptor-mediated Neurodegeneration, will be presented by Dr. Dennis W. Choi (St. Louis, MO).

The American Association of Neuropathologists is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians and designates the above continuing medical education activities for 23 credit hours in Category 1 of the Physician's Recognition Award of the American Medical Association. Participants should claim credit for only those sessions attended.


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The annual business meeting, to be held on Friday, June 22, and Saturday, June 23, will begin promptly at noon on both days.


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Hotel reservation cards and registration information will be mailed with the March 2001 Newsletter.


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2002: Marriott Denver City Center, Denver, CO June 19 - 24, 2002
2003: Wyndham Orlando Resort, Orlando, FL June 18 - 23, 2003

2000 ANNUAL MEETING--Atlanta, GA
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This year members will have the option of submitting abstracts electronically (online via our web page), or as in the past, by mail. Our Program Committee Chair, Dr. Jeff Golden, has been working closely with Allen Press to make electronic submission a reality this year. If submitted electronically, confirmation of receipt and notice of acceptance will be sent by e-mail. For those members wishing to submit abstracts as previously, customary blank blue sheets and postcards are included in this mailing.

Please submit your abstract by only one submission method (i.e., electronically or by mail, but not both).

Electronic submission should be available no later than January 7, 2001.

Regardless of the method of submissions, abstracts for the Chicago Meeting must be received by Friday, January 26, 2001. The Executive Council has instructed the Program Chair to refuse acceptance of any abstracts after this date THIS DEADLINE WILL BE STRICTLY ENFORCED.

Abstracts & Copyright Release/ Conflict of Interest Forms (enclosed)

For each abstract accepted for presentation at the Chicago meeting, regardless of the method of submission, a signed Copyright Release and Disclosure/Conflict of Interest forms must be on file. These should be signed by at least the first author and sent by regular mail to the Program Committee Chair.

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The 2000 AANP Membership Directory was mailed to all members in good standing with the August issue of the JNEN. Maintaining accurate up-to-date membership data is a major challenge that requires the cooperation of all members. If you have changes to your mailing address, phone, fax or e-mail, or if you recognize any inaccuracies, please contact the Secretary-Treasurer as soon as possible. Changes or additions also can be communicated on the 2001 dues notice form. To be included in the 2001 Membership Directory, your dues must be received no later than December 31, 2000.

Beginning January 2001, we plan to have an active online electronic Membership Directory. As discussed at the business meeting, this will be maintained by Allen Press and updated periodically (at least quarterly) by the Secretary-Treasurer. The online Directory will be similar in format to the printed (hard copy) edition that is published annually. Each member listing will include the Member Name, Degree, Membership Status, Department, Institution, Street Address, City, State, ZIP/ Postal Code, Country. Phone, Fax and e-mail. An example follows:

Doe, John, MD, PhD ACT
Department of Pathology
University of Anywhere
123 Smith St
Anywhere, US xxxxx
Phone: xxx-yyy-zzzz
Fax: xxx-yyy-zzz

If you wish to have your name included, please indicate this on the 2001 dues form where the question is posed, or please contact the Secretary-Treasurer. If you do not respond in the affirmative either on the dues form or by direct notification of the Secretary-Treasurer's office, you will not be listed in the internet directory. Your cooperation is appreciated.


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The International Society of Neuropathology and the British Neuropathological Society were delighted to welcome an international gathering of delegates at the XIVth International Congress of Neuropathology in Birmingham, UK, September 3-6, 2000. Congratulations to the organizers of a very stimulating, successful and enjoyable Congress.

The XVth International Congress of Neuropathology will be sponsored by the International Society of Neuropathology and the Italian Association of Neuropathology and will be held at the Lingotto Center, Turin, Italy, September 14-18, 2003. Additional information is available at the ISN website,


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The Seventh European Congress of Neuropathology, sponsored by the Scandinavian Neuropathological Society, will be held July 14-17, 2002 in Helsinki, Finland. A preliminary announcement of the meeting is included in this mailing. Additional information is available at the congress website,


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San Francisco, CA has been selected as the site of the XVIth International Congress in September 2006. The Congress to be sponsored by the AANP and the ISN will be held in early to mid September, although the exact dates are not yet firm. The San Francisco area offers a wealth of meeting sites and attractions and it is anticipated that this will be a popular meeting to attend. Details will be announced in the AANP Newsletter and posted on the AANP and ISN websites as they become available.


Clayton A. Wiley, M.D., Ph.D.

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Please take the time to read the AANP Professional Affairs Committee document enclosed in this mailing. This document provides the most up-to-date and accurate work-force data for Neuropathology. Obtaining these data remains a continual challenge. Any comments may be communicated to Dr. Wiley or any member of the Committee.


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CME notices were unavoidably delayed this year due to an unexpected difficulty with our bulk mail account. We apologize for any inconvenience this may have caused. The CME letters were included with the 2001 dues notices and mailed in mid October. If you did not receive your CME letter or believe that it is in error, please contact the Secretary-Treasurer at your earliest convenience.


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On October 23, 2000, Drs. Mark Cohen and Joe Parisi met in Cleveland with representatives from the Accreditation Council for Continuing Medical Education to renew accreditation for attendance at the Annual Meeting. Although official approval will not be known until Spring 2001, we already have instituted additional policies to ensure compliance with all ACCME guidelines. Also, beginning with the Chicago 2001 meeting, attendance at the Diagnostic Slide Session will qualify for an additional 3 hours of Category 1credit.


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As approved at the Business Meeting, dues for 2001 have been increased largely to off set increases in production costs of the Journal of Neuropathology and Experimental Neurology. Dues for active, associate and affiliate memberships are now $165, $155 and $140, respectively. Please note that this is the first increase in membership dues since 1990.

While AANP mailings and copies of JNEN are sent by relatively economical bulk mail to members residing within the United States, these must be sent by First Class Mail to Canadian and overseas members. The previous surcharges for members residing outside of the US no longer cover the ever-increasing mailing costs. For this reason, members in Canada will be charged an additional $16 and members outside of North America an additional $32 to cover mailing expenses.

Dues notices for 2001 were sent in mid-October. Members who have not paid their dues by December 31, 2000, will NOT be eligible for abstract acceptance, listing in the Directory, JNEN or Association mailings. If you have not received your dues notice, or if you believe that yours is inaccurate, please contact the Secretary-Treasurer as soon as possible.


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On a festive note, this year at the Annual Reception, a new and what we hope will become an annual event was instituted. The Door Prize, a sack of Sacagawea golden dollar coins, was taken home by Mrs. James E. McLaughlin of London, UK. We hope to be able to have additional door prizes provided by corporate sponsors in the future.


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It is with great sadness that we report the death of member, Dr. Kenneth A. Osterberg, who died at his home in Mentor, MN on October 16, 2000.


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Barbara H Amaker, MD
Daniel J Brat, MD, PhD
Daniel F Brown, MD*
Charleen T Chu, MD,PhD
Mel B Feany, MD, PhD
Robert A Garman, DVM **
Kenneth D Hutchins, MD
Catriona A McLean, MD
Hiroyuki Nakayama, DVM, PhD
Piero Parchi, MD
Ravi Raghavan, MD
Emilie Rouah, MD
Manfred Sell, MD
Yasuo Sugita, MD, PhD
Manuel F Utset, MD, PhD

*From AFFILIATE to ACTIVE membership
**From ASSOCIATE to ACTIVE membership



Reuben V Cuison, MD
Kar-Ming Fung, MD, PhD
Murat Gokden, MD
Tara Morrison, MD
Gina M Nelson, MD, PhD
John R Parker, MD
Alice B Schultz, MD
Pamela Bernadette Sequeira, MD
Jane H Uyehara-Lock, MD
Mary Beth Vono, MD



Sylvester Chidi Chima, MD
Linda M Dallasta, MD, PhD
Donald Lowell Price, Jr, MD
Masaki Takao, MD



Arthur K Asbury, MD
Larry J Embree, MD
Joel B Kirkpatrick, MD
Carl M Leventhal, MD
A Julio Martinez. MD
Franklin Robinson, MD
Marius P Valsamis, MD
Masazumi Adachi, MD


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  1. Minutes of the 2000 Annual Business Meeting
  2. Brief Biographical Sketch: William R. Markesbery, M.D.
  3. Diagnostic Slide Session Case Summaries
  4. Professional Affairs Report: Neuropathology Training
  5. Abstract Data Sheet (x1)
  6. Abstract Instructions (x1)
  7. Abstract Submission Form (blue sheet) (x2)
  8. Copyright Release Form & Conflict of Interest Statement (x1)
  9. Postcards for abstract confirmation of receipt and notice of acceptance (x2)
  10. Seventh European Congress of Neuropathology Announcement


American Association of Neuropathologists
Office of the Secretary-Treasurer
Department of Lab Medicine & Pathology
Mayo Clinic, 200 First Street S.W.
Rochester, MN 55905
Phone: (507) 284-3394
Fax:   (507) 284-1599
Home page:


Stephen J. DeArmond

Peter C. Burger

Dennis W. Dickson

Raymond A. Sobel

Vice-President for Professional Affairs
Clayton A. Wiley

Joseph E. Parisi

Assistant Secretary-Treasurer
Mark L. Cohen

Other Executive Council Members
Mauro C. Dal Canto
Bernardino Ghetti
Michael N. Hart
Susan S. Mirra
Jeannette J. Townsend
John Q. Trojanowski
Committee Chairs
Awards - Barbara J. Crain
Constitution - Thomas J. Montine
International Congresses - Bernardino Ghetti
Membership - Jonathan D. Fratkin
Professional Affairs - Clayton A. Wiley
Program - Jeffrey A. Golden
Richard Laverne Davis
International Society of Neuropathology Councilors
Mauro C. Dal Canto, M.D.
Hannah Chase Kinney, M.D.
David N. Louis, M.D., Ph.D.
Daniel P. Perl, M.D.
William O. Whetsell, Jr, M.D.
Official Journal
Journal of Neuropathology and Experimental Neurology

Editor - Michael N. Hart
Managing Editor - Eileen S. Healy
Newsletter Editor
Joseph E. Parisi
Copyright 2000, American Association of Neuropathologists © 2023