NEUROPATHOLOGY
NEWSLETTER
American Association of Neuropathologists
Volume 10, Number 3     October, 1999
IN THIS ISSUE
Highlights of the 1999 Annual Meeting
     Awards
Future Meetings
2000 Annual Meeting, Atlanta GA
     Registration Fees
     Scientific Sessions
     Special Course
     CME Credit
     Business Meeting
     Saul R. Korey Lecture
     Diagnostic Slide Session
     Presidential Symposium
     Matthew T. Moore Lecture
     Hotel Reservations
AANP News Items
     Notices
     Membership Directory
     Dues
     New JNEN Email Address
Professional Affairs Update
Birmingham in 2000
News from CAP
Discounts for AANP Members
New Members & Membership Changes
AANP & Newsletter Information

     Officers
     Other Executive Council Members
     Committee Chairs
     Journal & Newsletter


HIGHLIGHTS OF THE 1999 ANNUAL MEETING
(Portland, Oregon — June 17-20, 1999)

The Seventy-fifth Annual Meeting of the American Association of Neuropathologists was held at the Portland Hilton in Portland, Oregon from June 17-20, 1999.

The special course, Infectious Diseases of the Nervous System,organized by President Jeannette J. Townsend, included presentations by Drs. Leroy R. Sharer, Gareth D. H. Turner, Robert E. Mrak, Patricia K. Coyle, Arthur K. Asbury and Roger P. Simon. The Saul Korey Lecture, Key Participants in the Initiation of Inflammation in the Central Nervous System, was given by Dr. William F. Hickey.

The Presidential Symposium included the Presidential Address by Dr. Townsend entitled Herpes Simplex Virus. Dr. Richard T. Johnson served as the Matthew T. Moore Distinguished Lecturer and spoke on Viral Pathogenesis, an Overview. Other participants in the Presidential Symposium were Dr. Diane Griffin and Dr. Clayton A. Wiley who discussed Sindbis Virus, and Human Immunodeficiency Virus, respectively.

Dr. Lucy B. Rorke was the honored recipient of the Meritorious Service Award to Neuropathology.

At the meeting’s scientific sessions, a total of 226 abstracts were presented.

The 40th Annual Diagnostic Slide Session featured ten very interesting and challenging cases that stimulated considerable discussion.

Awards
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The Moore Award for the best clinicopathological correlation was presented to R. L. Davis, A. H. Tatum, A. E. Shrimpton, and P. D. Holohan from SUNY Health Science Center at Syracuse, for their paper Familial encephalopathy with neuroserpin inclusion bodies (FENIB): a new neurodegenerative syndrome. Honorable mentions for Moore Award were presented to A. P. Lieberman, J. Q. Trojanowski, D. G. B. Leonard, J. L. Barnett, J. Leverenz, Y. Robitaille, A. Malandrini, and K. H. Fischbeck for their paper Ataxia 1 and ataxia 3 in neuronal intranuclear inclusion disease, and to S. A. Back, N. S. Borenstein, J. J. Volpe, and H. C. Kinney for their paper, Immunocytochemical delineation of oligodendrocyte lineage in human cerebral white matter by confocal laser microscopy.

J. A. Golden and D. Heffron, from Children’s Hospital of Philadelphia and University of Pennsylvania, were awarded the Weil Award for the best paper in experimental neuropathology, for their presentation DM-Grasp is necessary for non-radial cell migration in the developing chick diencephalon. Recipients of honorable mentions for the Weil Award included S. A. Moore, R. Coral, R. D. Cohn, V. Straub, R. Williamson, and K. P. Campbell for their paper Severe muscular dystrophy and cardiomyopathy in mice deficient in delta-sarcoglycan, and to R. Chiesa, P. Piccardo, B. Ghetti, and D. A. Harris for their presentation Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.

Winners of the Rubinstein Award for the best paper in neuro-oncology were R. Amirnovin, J. Holash, S. Wiegand, G. Yancopoulos, M. Grumet, and D. Zagzag, from NYU Medical Center and Regeneron Pharmaceuticals, for their presentation Endothelial cell apoptosis and vascular regression in gliomas precede neovascularization: a new concept for glioma growth and angiogenesis.


FUTURE MEETINGS

2000:   Sheraton Atlanta Hotel (formerly, Radisson Hotel Atlanta), Atlanta, GA, June 8-11

2001:   Holiday Inn-Mart Plaza, Chicago, IL, June 21-24


2000 ANNUAL MEETING
Atlanta, Georgia — June 8-11, 2000

The 76th annual meeting of the American Association of Neuropathologists will take place on June 8-11, 2000, at the Sheraton Atlanta Hotel (formerly, Radisson Hotel Atlanta), Atlanta, GA. Abstracts will be published in the May, 2000 issue of The Journal of Neuropathology and Experimental Neurology.

Registration Fees
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  Member Non-member Trainee
General Registration $100 $150 $30
Special Course $125 $125 $125

As approved by the Executive Council, a registration fee has been instituted for all attendees of the Annual Meeting. The General Registration Fee is required for admittance to any function of the Association. This fee entitles you to attend all scientific sessions on Friday and Saturday, the Saturday evening Diagnostic Slide Session and the Sunday morning Presidential Symposium. An additional fee of $125 is required for admittance to the Special Course on Thursday, June 8.

Scientific Sessions
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Abstracts for the Atlanta Meeting must be received by Friday, January 14, 2000. Please refer to the Abstract Information Page for directions on completing and submitting the abstract forms. The abstract form, copies of the abstract, Copyright Release and Conflict of Interest forms (signed by the first author), Abstract Data Sheet, and completed (stamped) postcards should be sent to:

Bette K. Kleinschmidt-DeMasters, MD
Chair, AANP Program Committee
Univ. Colorado Health Sci. Center
Dept. of Pathology, B216
4200 E 9th Ave
Denver, CO 80262

Members who are sponsoring the abstract form of a non-member are asked to make certain that the authors have a copy of the instructions for abstract preparation and that the abstract form is properly prepared before signing it. As indicated in the instructions, the abstract must be signed by the Association member sponsoring the submission. Additional abstract forms may be obtained from the Secretary-Treasurer’s office upon request. Abstracts must be received by Friday, January 14, 2000. The Executive Council has instructed the Program Chair to refuse acceptance of any abstracts after this date.

Special Course (Thursday, June 8, 2000)
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The special course for the Atlanta meeting, entitled, The Hippocampus in Health and Disease, has been organized by President Suzanne S. Mirra and Bradley T. Hyman. An outstanding roster of speakers has been assembled. The program will include the following topics and speakers:

Introductory Remarks.  Suzanne S. Mirra (Brooklyn, NY)

Neuroanatomic Considerations of the Hippocampus and Parahippocampal Gyrus in the Human Brain.  Gary W. Van Hoesen (Iowa City, IA)

The Hippocampus and Alzheimer’s Disease.  Bradley T. Hyman (Boston, MA)

The Hippocampus in Other Neurodegenerative Disorders.  Dennis Dickson (Jacksonville, FL)

Clinical Studies of the Hippocampus in Aging and Alzheimer’s disease.  Ronald C. Petersen (Rochester, MN)

The Hippocampus, Memory, and Aging: Experimental Approaches.  Carol A. Barnes (Tucson, AZ)

The Medial Temporal Lobe, the Hippocampus and the Memory Systems of the Brain.  Larry R. Squire (La Jolla, CA)

The Hippocampus and Epilepsy.  Dawna L. Armstrong (Houston, TX)


CME Credit
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The American Association of Neuropathologists is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians. The Association certifies the Special Course as a continuing medical education activity and meets the criteria for 6 credit hours in Category I of the Physician’s Recognition Award of the American Medical Association.

Business Meeting
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The annual business meeting, to be held on Friday, June 9, and Saturday, June 10, will begin promptly at noon on both days.

Saul R. Korey Lecture
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Dr. Mary Case, Professor of Pathology at Washington University and Chief Medical Examiner of St. Louis County, has been selected as the next Saul R. Korey lecturer. Dr. Case’s lecture, entitled Neuropathology and Forensic Pathology: A Natural Synergism, will be presented on Saturday, June 10.

Presidential Symposium
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President Suzanne Mirra is organizing a stimulating symposium to be held Sunday, June 11.

Dr. Mirra’s Presidential Address will be entitled The Neuropathology of Alzheimer’s Disease: A Gray Matter. In addition, Dr. Douglas C. Wallace (Atlanta, GA) will speak on Mitochondrial Genetics and Neurodegeneration, and Dr. Maria Grazia Spillantini (Cambridge, UK) on Tau, Alpha-Synuclein, and Neurodegeneration. As part of the Symposium, the Matthew T. Moore Distinguished Lecture, entitled The Neuropathology of Drosophila, will be presented by Dr. Seymour Benzer (Pasadena, CA).

Diagnostic Slide Session
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The popular annual diagnostic slide session will be held at 8:00 PM on Saturday, June 10. Suitable cases for the Diagnostic Slide Session are being sought. If you have a case that you would like to present, please send the slides and a clinical summary to:

E. Tessa Hedley-Whyte, M.D.
Neuropathology
Massachusetts General Hospital
If your case is selected, it will be necessary to provide 150 slides for distribution. Cases will be selected before February 1, 2000. Protocols for the Diagnostic Slide Session will be available without charge at the meeting. For additional information, please contact Dr. Leroy Sharer.

Hotel Reservations and Meeting Registration
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The 2000 Meeting will be held at the Sheraton Atlanta Hotel (formerly, Radisson Hotel Atlanta). The hotel is located at 165 Courtland and International Boulevard, in the "heart" of downtown Atlanta. Hotel reservation may be made by calling 800-833-8624. When calling, please indicate that you are attending the AANP meeting to qualify for discounted room rates. Special rates for attendees of the meeting are as follows: $110 single occupancy, $120 double occupancy, $130 triple occupancy, $140 quad occupancy. These rates do not include 14% sales tax. Hotel reservation cards and additional registration information will be mailed with the March Newsletter.


AANP NEWS ITEMS

Notices
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It is with great sadness that we report the deaths of two revered members of the Association.

Any student of neurofibrillary pathology, cerebral amyloidosis, or the role of microglia in Alzheimer’s disease is familiar with the work of Dr. Henry Wisniewski, who died on Sunday, September 5, 1999 in New York City. Dr. Wisniewski served as the Director of the NYS Institute for Basic Research and was Professor of Pathology at S.U.N.Y. Health Science Center at Brooklyn. He will be remembered for his lively personality and his numerous contributions to neuropathology.

Dr. Humberto Cravioto, who died on Saturday, August 14, 1999, was a member of the Neuropathology faculty of New York University Medical Center for over 30 years. Although he retired from active practice in 1992, he remained a faithful attendee and participant in departmental conferences. Dr. Cravioto was among the first neuropathologists to describe the electron microscopic features of brain tumors in rodents and humans, and also was among the pioneers of tissue culture of human brain tumor cells.

Membership Directory
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The 1999 AANP Membership Directory was mailed to all members in good standing with the July issue of the JNEN. Several individuals inadvertently were omitted from the Directory and we apologize for any inconvenience this may have caused.

Included with the October 1999 Newsletter mailing is an insert containing the members who were not listed, and members with updated information. Maintaining accurate up-to-date membership data is a major task that requires the cooperation of all members. If you are NOT listed in the mailed Directory or in this insert, if there have been changes in your mailing address, phone, fax or e-mail, or if you recognize any inaccuracies, please contact the Secretary-Treasurer as soon as possible. Changes or additions also can be communicated on the 2000 dues notice form. Your cooperation is greatly appreciated.

To be included in the 2000 Membership Directory, your dues must be received no later than December 31, 1999.

The Association is planning to post the membership directory on the AANP home page. If you wish to have your name included, please indicate so on the 2000 dues form where the question is posed. If you do not respond in the affirmative either on the dues form or by direct notification of the Secretary-Treasurer’s office, you will not be listed in the internet directory.

Dues
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Dues notices for 2000 were sent in September. Members who have not paid their dues by December 31, 1999, will NOT be eligible for abstract acceptance, listing in the Directory, JNEN or Association mailings. If you have not received your dues notice, or if you believe that yours is inaccurate, please contact the Secretary-Treasurer as soon as possible.

New JNEN E-mail Address
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Please note that the e-mail address for the Journal of Neuropathology and Experimental Neurology has changed.


PROFESSIONAL AFFAIRS UPDATE
Clayton A. Wiley, M.D., Ph.D.
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As many of you will recall, the AANP Professional Affairs Committee is performing an outcomes survey of the Neuropathology Training Programs in the United States. The American Association of Medical Colleges (AAMC) maintains a database of physician work-force statistics that include Neuropathology. The AAMC database shows a total of 46 accredited Neuropathology training programs, with 38 active trainees. While the AAMC has attempted to survey this nascent work-force, the response rate has been poor and thus it is difficult to obtain a clear picture of the work-force needs of our specialty.

At the June 1999 meeting of the AANP, the Committee reviewed the initial returns from the AANP Professional Affairs Committee survey of Neuropathology training programs. At the time a total of 25 programs had responded. At the committee meeting, additional programs were identified and new surveys subsequently sent. To date, a total of 28 of 46 accredited programs have responded and identified 99 residents trained in Neuropathology in the past 5 years.

The second phase of the project involved surveying all of the identified Neuropathology fellows. To date, of the 99 fellows identified, 53 have completed the survey, 7 had inadequate address to guarantee receipt of the survey, and 36 did not or would not respond despite multiple mailings and phones calls. The Committee plans on reviewing the completed surveys and submitting a full report and analysis to the Executive Committee of the AANP and the Journal of Neuropathology and Experimental Neurology at the beginning of the year.


BIRMINGHAM IN 2000
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A preliminary program of the XIVth International Congress of Neuropathology has been published on the Congress website. The call for abstracts will be circulated in mid-November with a closing date of March 17, 2000.

The Congress will take place September 3-6, 2000 in Birmingham, UK. Plenary and Scientific Sessions will feature presentations by distinguished speakers, as well as workshops for in-depth discussion. Some highlights include the following lectures and symposia:

  • Tau and a-synuclein in Alzheimer’s disease and related disorders.
  • Muscle disorders with genetic defects of "structural" proteins (dystrophies and some congenital myopathies)
  • Cerebrovascular disease and trauma
  • Molecular genetic abnormalities in gliomas
  • Neuropathology of psychoses
  • Prion diseases in the 21st century
  • Pathogenesis of demyelination and its consequences for remyelination
  • Neurodevelopmental genetics and embryonal tumors of the nervous system
  • Myelin pathology and hereditary motosensory neuropathies
  • Inflammatory disorders of the CNS
  • Oxidative stress and mitochondrial factors in Parkinson’s disease, Alzheimer’s disease and amyotrophic lateral sclerosis
  • Stem cells and neurotransplantation

For details and further information, visit the Congress website: www.neuropathology2000.co.uk.

For information about the Congress, and registration and abstract forms, contact:

Congress Secretariat ICNP 2000
c/o Concorde Services Ltd


Scientific inquiries should be directed to Dr. Weller, Chair of the Scientific Committee:
Professor Roy O. Weller
Dept Pathology (Neuropathology)
Southampton Univ School of Medicine


NEWS FROM CAP
Barbara J. Crain, M.D., Ph.D.
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The College of American Pathologists (CAP) is the largest pathology society in the United States; the College, in fact, is larger than any other medical specialty group and is second in size only to the AMA amongst general medical societies. Within the CAP, the subspecialty of neuropathology is represented by the Neuropathology Committee.

Current activities of the Neuropathology Committee include the preparation of Kodachrome-based study sets in diagnostic neuropathology (which may be used either for CME credits or teaching archives), the presentation of neuropathology seminars at national CAP meetings, and the formal representation of neuropathology’s interests in general affairs of the CAP. In January 2000, Dr. Barbara Crain will succeed Dr. Gary Pearl as committee chair and Dr. Joe Parisi will become vice-chair. Please contact one of them if you have questions about CAP activities, or if there are issues you would like raised within the CAP.


DISCOUNTS FOR AANP MEMBERS
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Discounted subscription rates for the following journals are being extended to AANP members.

IOS Press is offering a one-year subscription of the Journal of Alzheimer’s Disease for US$116 (shipping and handling included). The journal is edited by AANP members, Drs. George Perry and Mark A. Smith (Case Western Reserve University). If you would like a free sample copy, or would like to subscribe) or visit the ISO website: www.iospress.nl.

A one-year subscription to Neuropathology & Applied Neurobiology is available from Blackwell Science for US$156 (shipping and handling included). Additional information is available from the website: www.blackwell-science.com



NEW MEMBERS &
CHANGES IN MEMBERSHIP STATUS

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    Active
Philip Boyer
Henry Brown
Mary Case
Sandra Cottingham
Mark Curtis
John Donahue*
Robert Hevner
Particia Kirby
James E. McLaughlin
Alan L. Morrison
Anders Paetau
George Perry**
Marie-Madeline Ruchoux
Tarik Tihan
Anne Vital
Claude Vital
Serge Weis
    Associate
Xiaodan Cai
Masako Taniike

    Affiliate
Mark R. Matthews
Jennifer McKay
James Primavera

    Senior
Mary W. Ambler
George Collins
Margorie B. Lees
Haruo Okazaki
Henry DeF Webster


*From Affiliate to Active Membership
**From Associate to Active Membership

AANP & NEWSLETTER INFORMATION

American Association of Neuropathologists
Office of the Secretary-Treasurer
Department of Lab Medicine & Pathology
Mayo Clinic, 200 First Street S.W.
Rochester, MN 55905
Email: info@aanp-jnen.com.
Home page: www.aanp-jnen.com
 

President
Suzanne S. Mirra

Vice-President
Dawna L. Armstrong

President-Elect
Stephen J. De Armond

Vice-President-Elect
Peter C. Burger

Vice-President for Professional Affairs
Clayton A. Wiley

Joseph E. Parisi
Secretary-Treasurer

Assistant Secretary-Treasurer
Mark L. Cohen

Other Executive Council Members
Mauro C. Dal Canto
Dennis W. Dickson
Bernardino Ghetti
Michael N. Hart
E. Tessa Hedley-Whyte
Jeannette J. Townsend
John Q. Trojanowski
 
Councilors to the International Society of Neuropathology
Mauro C. Dal Canto, M.D.
Hannah Chase Kinney, M.D.
David N. Louis, M.D., Ph.D.
Daniel P. Perl, M.D.
William O. Whetsell, Jr, M.D.
 
Committee Chairs
Awards - Barbara J. Crain
Constitution - Thomas J. Montine
International Congresses - Bernardino Ghetti
Membership - Jonathan D. Fratkin
Professional Affairs - Clayton A. Wiley
Program - Bette K. Kleinschmidt-DeMasters
 
Official Journal
Journal of Neuropathology and Experimental Neurology

Editor - Michael N. Hart

 
Newsletter Editor
Joseph E. Parisi
Copyright © 1999, American Association of Neuropathologists