Awards for Meritorious Contributions to Neuropathology Weil Award for Best Paper on Experimental Neuropathology Presented at the Annual Meeting Moore Award for Best Paper on Clinico-Pathological Correlation Presented at the Annual Meeting Rubinstein Award for Best Paper on Neuro-oncology Presented at the Annual Meeting Awards for Meritorious Contributions to Neuropathology Year Name 1959 Armando Ferraro Arthur Weil 1960 Joseph Globus George Hassin 1968 Paul Yakovlev Abner Wolf Harry Zimmerman 1970 Webb Haymaker 1971 James Kernohan 1972 George Jervis 1979 Raymond Adams David Cowen Matthew Moore 1981 Richard Lindenberg 1983 Orville Bailey 1984 Margaret Murray 1985 Kenneth Earle Leon Roizin Nathan Malamud 1986 Martin Netsky 1987 No Award Presented 1988 E. P. Richardson, Jr. F. Stephen Vogel 1989 Lucien J. Rubinstein Robert D. Terry 1990 Ellsworth C. Alvord, Jr 1991 Lysia K. S. Forno 1992 John Moossy Gabriele M. Zu Rhein 1993 Peter Lampert Elias Manuelidis 1994 Murray Bornstein Lowell Lapham Samuel Hicks 1995 Asao Hirano Amico Bignami 1996 Franz Seitelberger Pasquale Cancilla 1997 Henryk M Wisniewski 1998 Richard L. Davis Wolfgang Zeman 1999 Lucy B. Rorke 2000 William R. Markesbery 2001 John J, Kepes Henry de Forest Webster Weil Award for Best Paper on Experimental Neuropathology Presented at the Annual Meeting Year Author Title 1959 J.H. Austin Experimental Histopathological Studies in Metachromatic Leucoencephalopathy 1960 H. de F. Webster, D. Spiro, B. Waksman and R.D. Adams Phase and Electron Microscope Study of Experimental Diphtheritic Neuritis in Guinea Pig Sciatic Nerve 1961 A., Hirano, N. Malamud and L.T. Kurland Parkinsonism-Dementia Complex, an Endemic Disease on the Island of Guam, Pathologic Features 1962 F.P. Aleu, R. Katzman and R.D. Terry Fine Structure and Electrolyte Analysis of Cerebral Edema Produced by Triethyl Tin 1963 F.L. Edelman, F. Aleu, L.C. Scheinberg, , J.C. Evans and L.M. Davidoff Effect of X-Irradiation on the Growth of Intracerebral Gliomas in Mice 1964 F. Ikuta and H.M. Zimmerman Observations on Lesions Induced by Carcinogenic Hydrocarbons 1965 I. Klatzo and O. Steinwall Observations on Behaviour of Blood-Brain Barrier in the Cerebrospinal Fluid Pathways in Sharks 1966 B.Q. Banker A Phase and Electron Microscopic Study of Dystrophic Muscle 1967 R.T. Johnson and K.P.Johnson Hydrocephalus as a Sequela of Experimental Mumps Virus Infection in the Hamster 1968 R.M. Herndon G. Margolis, and L. Kilham Virus Induced Cerebellar Malformation. An Electron Microscopic Study 1969 C. Raine, H. Wisniewski and J. Prineas Patterns of Remyelination in Chronic Experimental Allergic Encephalomyelitis 1970 K. Suzuki and K. Suzuki Krabbe's Globoid Cell Leukodystrophy: Deficiency of Galactocerebroside Beta-Galactosidase Activity 1971 A. Koestner, J.M. George, and J.F. Long Neurosecretory Activity of the Canine Supraoptic Nucleus in vivo and in vitro 1972 J.B. Penny, L.P. Weiner, R.M. Herndon, and O. Narayan Direct Serological Identification of Virions from Progressive Multifocal Leucoencephalopathy by Electron Microscopy 1973 G.M. ZuRhein, A.E. Albert, B.L. Padgett, D.L. Walker, and R.F. Marsh, Pathology of Brain Tumors Induced in Syrian Hamsters after Inoculation with a Papovavirus (JC) from Human Brain Tissue 1974 S.R. VandenBerg, M.M Herman, A.M. Spence, J.C. Sipe, S. Ludwin and A Bignami An Experimental Mouse Testicular Teratoma as a Model for Neuroepithelial Neoplasia and Differentiation 1975 P.S. Spencer H.J. Weinberg, C.S. Raine and J.W. Prineas The Perineurial Window—A New Model to Study Demyelination and Remyelination 1976 S. Nag, D.M. Robertson and H.B. Dinsdale Blood-Brain Barrier Alterations in Acute Experimental Hyper tension: Ultrastructural Studies 1977 A.J. Aguayo, K. Mizuno and G.M. Bray Schwann Cell Transplantation: Evidence for a Primary Sheath Cell Disorder Causing Hypomyelination in Quaking Mice 1978 NO AWARD PRESENTED   1979 S.K. Ludwin Failure of Adequate Central Remyelination Following Longterm Demyelination by Cuprizone 1979 J.D. Fratkin, L.E. DeBault and P.A. Cancilla Platelet-Induced Mitogenic Stimulation of Mouse Cerebral Vascular Endothelium 1980 M.Z. Jones, J.G. Cunningham, A.W. Dade, G. Dawson and D.M. Alessi Caprine Oligosaccharide Storage Disorder 1981 M.N. Hart and K.L. Sadewasser Effects of Specifically Activated Lymphocytes on Brain Endothelium 1982 M. Rodriguez, P. Lampert, M. Buchmeier and M. Oldstone Ultrastructural Localization of Viral Antigen in Mice Persistently Infected with Lymphocytic Choriomeningitis Virus (LCMV) 1983 A Bizzi, R. Crane, M. Yoon, L. Autilio-Gambetti and P. Gambetti The Axonal Transport of Neurofilaments is Impaired in Aluminum Intoxication 1984 L.E. Davis and M. Kornfeld Influenza B Virus Model of Reye's Syndrome: Evidence for a Defective Infection in Mice 1985 R.L. Schelper, E. Whitters and M.N. Hart, True Microglia Distinguished from Macrophages by Specific Lectin Binding 1986 B. Trapp, M. Pulley, L. Cork, G. Scangos, J. Sima, G. Jay and G. Khoury Dysmyelination in Transgenic Mice Containing the Early Region of JC Virus 1987 Seth Love Distribution of Theiler's Virus in the CNS of Athymic Nude Mice: Effect of Varying the Route of Inoculation 1988 V Lee, L. Otvos, M. Schmidt and J. Trojanowski Immunological Similarities Between Multiphosphorylation Repeats in the Large Neurofilament (NF) Proteins and Neurofibrillary Tangles (NFTs) 1989 A. Messing, R.R. Behringer, J.P. Hammang, G. Lemke, R.L. Brinster and R.D. Palmiter Schwann-Cell-Specific Gene Expression in Transgenic Mice 1990 L. Mucke, M.D. Norenberg and M.B. Oldstone Use of the Murine Glial Fibrillary Acidic Protein (GFAP) Gene to Target Expression of Hybrid Genes to the CNS: Astrocyte Specific Expression in Transgenic Mice 1991 L.C. Ang, B. Bhaumick and B. Juurlink Effect of Astrocytes, Insulin, and Insulin Growth Factor I(IGF-I) on the Survival of Motor Neuron Cultures 1992 H.B. Clark, R.M. Feddersen, R. Ehlenfeldt, W.S. Yunis and H.T. Orr SV40T Antigen-induced Transgenic Murine Models of Cerebellar Ataxia 1993 J.F. Goodrum, T.S. Earnhardt, N.D. Goines and T.W. Bouldin Fate of Myelin Lipids During Nerve Degeneration 1994 R.W. Shin, V.M.Y. Lee, and J.Q. Trojanowski Aluminum Modifies the Properties of Alzheimer PHFE 1995 K.A. Roth, N. Motoyama and D.Y. Loh In vivo and In vitro Studies of BCL-X-deficient Mice 1996 Phyllis L. Faust and Mary E. Hatten Production of a Mouse Model for Zellweger Syndrome, a Neuronal Migration Disorder 1997 Jeffrey A. Golden Sonic Hedgehog Protein in the Chick Dorsal Anterior Neural Tube Disrupts Cranial Neural Crest Formation, Eye Development and Patterning in the Brain 1997 Robert F. Hevner, S. Smiga, A. Bulfone, J.J. Meneses, R.A. Pedersen and J.L.R. Rubenstein Abnormal Cortical Organization and Connections in Mice with Targeted Mutation of the TBR-1 Gene 1998 E.J. Huang and L.F. Reichardt Neurotropin-3 Modulates Expression of the POU Domain Factor BRN-3A in Early Sensory Gangliogenesis 1999 J.A. Golden and D. Heffron DM-Grasp is Necessary for Non-radial Cell Migration in the Developing Chick Diencephalon 2000 L. Refolo, K. Duff, B. Malester, J. LaFrancois, R. Wang, K. Sambamurti, G.S. Tint, T. Thomas and M.A. Pappolla Hypercholesterolemia Accelerates Amyloid Accumulation in a Transgenic Mouse Model of Alzheimer's Disease 2001 S. A. Moore, F. Saito, M. Henry, A. Messing, R. D. Cohn, R. Williamson, and K. P. Campbell Selective Deletion of Brain Dystroglycan Results in Neuronal Migration Error   Moore Award for Best Paper on Clinico-Pathological Correlation Presented at the Annual Meeting Year Author Title 1971 S.M. Chou, R. Burell, J. Harley, L. Gutman and R. Roos Subacute Focal Adenovirus Encephalitis 1972 C.L. Moore, Valsamis M.P. A.B Johnson, S Goldfischer, R.H. Ritch, H. Wisniewski, W.T. Norton, I. Rapin and L. Gartner Cerebrohepatorenal Syndrome: A Defect in Oxidative Metabolism 1973 K. Iqbal, I. Grundke-Iqbal, M.L. Shelanski and I. Tellez-Nagel Abnormal Proteins in Huntington's Disease 1974 J.Richard Baringer Recovery of Herpes Simplex Virus from Human Sacral Ganglion 1975 M. Igarashi, H.H. Schaumburg, J.M. Powers, Y. Kishimoto, E.H. Kolodny and K. Suzuki Fatty Acid Abnormality in Adreno-Leukodystrophy (ALD) 1976 H.H. Schaumburg, J.M. Powers, P.S. Spencer, C.S Raine., J.W. Prineas and D.W.Boehme The Myeloneuropathy Variant of Adrenoleukodystrophy 1977 J.M. Powers and S.S. Spicer Histochemical Characteristics of Cerebral Amyloid 1978 NO AWARD PRESENTED   1979 K. Sahashi, A.G. Engel, E.H. Lampert and F.M. Howard Ultrastructural Localization of the Terminal and Lytic Ninth Complement (C9) at the Motor End-Plate in Myasthenia Gravis 1979 L.E. Davis, L. Johnsson and M. Kornfeld Virologic, Microscopic and Immunofluorescent Studies of Human Inner Ears Infected with Cytomegalovirus 1980 M. Adachi, S.E. Brooks, L.M Hoffman, D. Amsterdam and L. Schneck Fine Structural Features of Tay-Sach's Disease Brain Cells in vitro After Long-Term Treatment with Concanavalin A and Hexosaminidase A 1981 J.M Powers, W.W. Schlaepfer, M.C. Willingham and B.J.Hall An Immunoperoxidase Study of Senile Cerebral Amyloid 1982 H. Budka, and K.V. Shah Papova Viral Antigens in PML Brains 1983 J.E. Greenlee, C. del Cerro and R.M. Herndon Immunological Labelling of Purkinje Cells with Sera from Patients with Paraneoplastic Cerebellar Degeneration and Ovarian Carcinoma 1984 M. Adachi, S.E. Brooks, M.R. Stein, L.M. Hoffman and L.Schneck The Effects on Human Retinoblastoma Cells in-vitro and in-vivo After Exposure to the E Variant of Encephalomyocarditis Virus (EMC-E) 1985 C.A. Wiley, R. Schrier, F. Denaro, J. Nelson, P. Lampert and M. Oldstone Localization within the CNS of Cytomegalovirus Proteins and Genome During Fulminant Infection in an AIDS Patient 1986 H.H. Goebel, J. Bohl, B. Tettenborn, G. Kramer, H.G. Fromme and P.G. Schmidt Polyneuropathy Due to Acute Arsenic Poisoning 1987 A.A.F. Sima, V. Nathaniel, V. Bril and D.A. Greene, H.C. Kinney, C.K. Ottoson and W.F. White The Effect of Aldose Reductase Inhibition on Human Diabetic Neuropathy Three-Dimensional (3-D) Autoradiographic Localization of Opiate Receptor Binding in Human Infant Brainstem 1988 N. Kowall, M. Kennedy and K.Kosik Allocortical Projection Neurons Predisposed to Neurofibrillary Tangle Formation are Enriched in Type II Ca/calmodulin-dependent Protein Kinase 1989 D. Wolfe, D. Schindler, R. Desnick and D. Perl Infantile Neuroaxonal Dystrophy (INAD) Associated with a Lysosomal Enzyme Deficiency 1990 A.C. McKee, K.S. Kosik and N.W. Kowall Dystrophic Neurites in the Neocortex are the Critical Neuropathological Correlate of Dementia in Alzheimer's Disease 1991 J.A.R. Nicoll and S. Love Burnt Out Herpes Simplex Encephalitis: Use of the Polymerase Chain Reaction to Detect Viral DNA 1992 E.A. Nimchinsky, P.R. Hof, J. Nasrallah, D.P. Perl, J.C. Steele, D. Purohit, A. Delacourte and J.H. Morrison, Chemoarchitecture of the Cerebral Cortex in Guam ALS/Parkinsonism-Dementia (ALS/PD) 1993 M.T. Curtis, J.A. Mastrianni, J.Y. Garbern and J.C. Oberholtzer An American Form of Gerstmann-Straussler-Scheinker Disease with Abundant Cerebellar Plaques 1994 A. Perry, V. Tonk, D.D. McIntire and C.L. White Interphase Cytogenetic (In Situ Hybridization) Analysis of Astrocytomes Using Archival Formalin-Fixed, Paraffin-Embedded Tissue and Light Microscopy 1995 B. Ghetti, P. Piccardo, Y. Ichimiya, M. Goedert, T. Kitamoto, J. Tateishi, M.G. Spillantini, B. Frangione, O. Bugiani, G. Giaccone, F. Prelli, S.R. Dlouhy and F. Tagliavini Prion Protein Amyloid Angiopathy and Alzheimer Neurofibrillary Tangles in PRNP Stop Codon 145 1996 Anthony T. Yachnis and Thomas A. Eskin Distinct Developmental Programs of BCL-2 and BCL-X are Altered in Glioneuronal ''Hamartias" of the Temporal Lobe 1997 Daniel J. Brat, B.W. Scheithauer, S.C. Cortez, K. Brecher and P.C. Burger Third Ventricular 'Chordoid Glioma': A Distinct Clinicopathologic Entity 1998 Venkat R. Challa, D.M. Moody, W.R. Brown, D.M. Reboussin, M.A. Lovell and W.R. Markesbery Recent Developments in the Pathology of Brain Injury during Human and Experimental Cardiopulmonary Bypass 1998 Marla Gearing, J.R. Murrell, M.G. Spillantini, M. Goedert, R.A. Crowther, A.I. Levey, R. Jones, W. Walton, J.M. Shoffner, B.H. Wainer, M.L. Schmidt, J.Q. Trojanowski, B. Ghetti and S.S. Mirra Tau Cytopathology in a Patient with Familial Early Onset Dementia and a Mutation in the Tau Gene 1999 R.L. Davis, A.H. Tatum, A.E. Shrimpton and P.D. Holohan Familial Encephalopathy with Neuroserpin Inclusion Bodies(FENIB): A New Neurodegenerative Syndrome 2000 A. Messing, A.B. Johnson, O. Boespflug-Tanguy, D. Rodriguez, J.E. Goldman and M. Brenner Mutations of GFAP Associated with Alexander Disease 2001 R. Vidal, M.D. Benson, J. J. Liepnieks, M. Yazaki, L. Miravalle, E. Uro-Coste, M. B. Delisle and B. Ghetti A Neurodegenerative Disease with Intranuclear Protein Deposits:Electron Microscopic and Biochemical Studies     Rubinstein Award for Best Paper on Neuro-oncology Presented at the Annual Meeting Year Author Title 1991 Mark R. Hurtt, John Moossy, Maryann Donovan-Peluso and Joseph Locker Epidermal Growth Factor Gene Amplification in Gliomas: Histopathology, Clinical Features and Prognosis 1992 M.L. Rodriguez, N. Jensen and C.A. Miller Malignant Schwannomas in Transgenic Mice 1993 D.N. Louis, M.P. Rubio, K. Correa, A. von Deimling and J.F. Gusella Molecular Genetic Alterations in Pediatric Brain Stem Gliomas 1994 K. Heck, P. Pyle, and J.M. Bruner Bc1-2 Expression in Cerebellar Medulloblastomas 1995 W.H. Wong, D. Chou, K. Ueki, A. von Deimling and D.N. Louis The Chromosome l9q Glioma Tumor Suppressor Gene: Deletion Mapping and Candidate Genes 1996 Hiroki Ohgaki, K. Wantanabe, O. Tachiband, K. Sato and P. Kleihues Overexpression of the EGF Receptor and p53 Mutations are Mutually Exclusive in the Evolution of Primary and Secondary Glioblastomas 1997 Candece L. Gladson, Vivian Pijuan-Thompson and J. Robert Grammer PDGF Stimulation of Glioblastoma Cells Alters the Cellular Localization of Integrin avbp3 Adhesion Plaques and Increases avbp3-mediated Cell Migration 1998 BetteKay Kleinschmidt-DeMasters, L.C. Evans, M.A. Bitter and K.R. Shroyer Telomerase Expression in Cerebrospinal Fluid as an Adjunct to Cytologic Diagnosis 1999 R. Amirnovin, J. Holash, S. Wiegand, G. Yancopoulos, M. Grumet and D. Zagzag Endothelial Cell Apoptosis and Vascular Regression in Gliomas Precede Neovascularization: A New Concept for Glioma Growth and Angiogenesis 2000 G.N. Fuller, K.R. Hess, C.H. Rhee, J.M. Bruner, R.A. Sawaya, W.K.A. Yung, and W. Zhang Molecular Classification of Human Gliomas by Gene Expression Profiling 2001 H. Ohgaki, M. Nakamura, T. Watanabe and P. Kleihues Promoter Hypermethylation of O6-Methylguanine-DNA Methyltransferase Gene in Gliomas